VF Bioscience Health Ingredients

Premium, clinically validated products

“Empowering life with Nature’s resources” is the mission of our partner Amino Up Co. Based in Sapporo on the Japanese island of Hokkaido, Amino Up produces bioactive substances from natural sources. Amino Up and VF Bioscience share the same philosophy : offer only exclusive, carefully developed ingredients with proven efficacy. AHCC® and ETAS® are among the best clinically-validated ingredients on the market, with more than 100 published scientific studies referenced on Pubmed, involving more than 80 universities and research institutes worldwide. We are proud to make these innovative, valuable products available to European consumers.

AHCC® – Shiitake alpha-glucans for immune support

AHCC® is a standardized preparation of alpha-glucans. These small immunomodulatory polysaccharides, easily absorbed by the organism, are produced by Shiitake cells during a proprietary cell culture process. AHCC® is Japan’s top-selling immune support ingredient, its properties have been described in more than 100 scientific articles, including reports of more than 30 human clinical studies.

ETAS® – Asparagus extract for stress relief, sleep and cognitive function

ETAS® is a standardized asparagus extract which alleviates the effects of stress by controlling the levels of cortisol. ETAS® also shows a clinically validated efficacy for sleep improvement, support of mood and cognitive function, and protection of neuronal cells. ETAS® active components are natural molecules with a capacity to induce cytoprotective heat-shock proteins.

News and Posts

AHCC® Research

Research from Yale University, USA, shows that AHCC® promotes the effects of Immune Checkpoint Inhibitors (PD-1/CTLA-4 inhibitors) in a murine colon cancer model (Park et al. Frontiers in Immunology 2022).

ICNIM 2025

The annual International Conference on Nutrition and Integrative Medicine (ICNIM) will be held in Sapporo, Japan, on November 7-10, 2025.

A strict commitment to quality and safety

AHCC® and ETAS® production processes comply with strict quality assurance procedures to guarantee perfect safety and clinical efficacy.